#10 Kunal Nayyar aka Raj Koothrappali
Acting as Rajesh Koothrappali, his character is an innovative and original character on "The Big Bang Theory". In the show, he is is an Indian astrophysicist who hates Indian food and likes ‘Sex and the City’ and Sandra Bullock films.

#9 Jim Parsons aka Sheldon Cooper
A quirky Caltech physicist, Jim's character Cooper is popularly appreciated as the breakout member of ‘The Big Bang Theory’ team behind the show debut.

#8 Kaley Cuoco aka Penny
Presenting to us the character of Penny, Kaley's character hits up a new friendship with nerdy neighbours Sheldon and Leonard.

#7 Johnny Galecki aka Leonard Hofstadter
Bringing to life the role of Leonard Hofstadter, his character is an associate physicist at Caltech.

#6 Mayim Bialik aka Amy Farrah Fowler
Mayim plays the role of Amy Farrah Fowler in the series. Interestingly, she has obtained a doctorate in neuroscience in actual life. Dr Amy gets paired with Sheldon on a dating website in season 4 and the two date during the entire series.

#5 Simon Helberg aka Howard Wolowitz
As an MIT grad who survived with his mum for some seasons, Simon did the belt-buckle-loving aerospace technician, which is truly one of the show’s memorable, witty parts.

#4 Carol Ann Susi aka Debbie Wolowitz
I am sure everyone remembers this iconic actor Carol Ann Susi. Unfortunately, she died of cancer in the year 2014 but her role in this sitcom will always be remembered. She was the voice behind the recurring unseen character of Mrs Wolowitz.

#3 Melissa Rauch aka Bernadette Rostenkowski
Her character in the sitcom series works at ‘The Cheesecake Factory’ and is studying to earn her PhD in microbiology. She is kind and has a voice like a kewpie doll might.

#2 Kevin Sussman aka Stuart Bloom
After making his debut on the ‘The Big Bang Theory’ in the season two, he was constantly present on the set. He was advanced to a series established star for season six, however, is now scheduled as return character.

#1 John Ross Bowie aka Barry Kripke
A Plasma physicist at the California Institute, John's character Barry is no less than an antagonist to other four guys. His character is surely very annoying who never misses a chance to make fun of others.